CCND3 ELISA Kit for Bovine(Bos taurus) | EIAab.comCCND3 ELISA Kit for Bovine(Bos taurus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > CCND3(Gene name) > Bovine

CCND3 (Gene name),

G1/S-specific cyclin-D3 (Protein name ), CCND3_BOVIN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

CCND3;

Protein name:

G1/S-specific cyclin-D3;

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts with the CDK4 and CDK6 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Component of the ternary complex cyclin D/CDK4/CDKN1B required for nuclear translocation and modulation of CDK4-mediated kinase activity. Can form similar complexes with either CDKN1A or CDKN2A. Interacts with ATF5 and EIF3K.

Function:

Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

Subcellular Location:

Nucleus Cytoplasm Membrane Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated to the nucleus through interaction with KIP/CIP family members.

Protein Attributes:

Sequence length:

292

Sequence:

50:

100:

150:

200:

250:

292:

LRESLREAAQ | TSPSPAPKAP | RGSSSQGPSQ | TSTPTDVTAI | HL

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

Q3MHH5

UniGene:

Bt.29057

STRING:

9913.ENSBTAP00000035894

Pfam:

PF02984

KEGG:

bta:540547

Uniprot:

Q3MHH5

FOR

ELISA Kit for Bovine G1/S-specific cyclin-D3

Cat.:

E0587h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Bovine G1/S-specific cyclin-D3

Cat.:

E0587m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Bovine G1/S-specific cyclin-D3

Cat.:

E0587b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Bovine G1/S-specific cyclin-D3

Cat.:

E0587r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine G1/S-specific cyclin-D3

Cat.:

U0587b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine G1/S-specific cyclin-D3

Cat.:

U0587h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine G1/S-specific cyclin-D3

Cat.:

U0587m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine G1/S-specific cyclin-D3

Cat.:

U0587r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Bovine G1/S-specific cyclin-D3

Cat.:

P0587Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine G1/S-specific cyclin-D3

Cat.:

P0587Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine G1/S-specific cyclin-D3

Cat.:

P0587Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Bovine G1/S-specific cyclin-D3

Protein for Bovine G1/S-specific cyclin-D3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Thymus.

Product Feedback Wall

* Email:
*Comments: